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        Christian McCaffrey "Likely" To Play Week 1

        By Jared Smola | Updated on Sat, Sep 6 2025 7:50 PM UTC
        Christian McCaffrey Headshot

        49ers RB Christian McCaffrey (calf) is "likely" to play vs. the Seahawks on Sunday, according to NFL Network's Ian Rapoport.

        What They're Saying

        The full report from Rapoport: "49ers RB Christian McCaffrey is questionable with a calf injury, but signs are pointing to him playing vs the Seahawks, per The Insiders. McCaffrey was running around on the side during practice Friday and was optimistic to reporters. Barring a setback, it’s likely he’ll go."

        2025 Fantasy Football Impact

        Vibes have been relatively good on McCaffrey since Friday afternoon. He did a pretty extensive warmup prior to practice that day and sounded optimistic about his Week 1 status afterward.

        There's still elevated risk here, particularly in the form of an in-game setback. But McCaffrey will be impossible to keep out of fantasy lineups unless we get a report of him being on some type of snap count.

        We'll continue to keep you updated on his status.

        Jared Smola Author Image
        Jared Smola, Lead Analyst
        Jared has been with Draft Sharks since 2007. He’s now Lead Analyst, heading up the preseason and weekly projections that fuel your Draft War Room and in-season tools. He currently ranks ninth among 173 analysts in draft rankings accuracy.

        In This Article

        Christian McCaffrey
        SF RB
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