Colts WRs Josh Downs (concussion) and Ashton Dulin (chest) are out for Sunday’s game vs. the Chargers. Michael Pittman and Alec Pierce will continue to operate as the top two WRs, but the Colts might now be forced to rely on WR Adonai Mitchell in a significant role. Anthony Gould is the only other WR on the active roster. Laquon Treadwell is on the practice squad.

We learned ahead of Sunday's game that Colts WR Adonai Mitchell would play a limited role against the Raiders after marring his Week 4 opportunity with multiple stupid mistakes. That proved true, as Mitchell played just six snaps and ran two routes against the Raiders. He ranked fifth in playing time among Colts WRs, even with Alex Pierce still out. Ashton Dulin got the group's biggest boost, matching Michael Pittman Jr.'s team-high 27 routes, according to Pro Football Focus. Josh Downs trailed narrowly at 23 routes.

Colts WR Alec Pierce (foot) did not practice on Wednesday. We don't have any details on his foot injury. WR Josh Downs (shoulder) is not expected to play vs. the Patriots this weekend, while WR Ashton Dulin (ankle) also missed Wednesday's practice. That leaves Michael Pittman, Adonai Mitchell, and Anthony Gould as the three healthy WRs on Indianapolis' active roster.