The Cardinals somehow managed to let Broncos RB Latavius Murray run for 130 yards and a TD on 24 carries in Sunday's Denver victory. Murray hit runs of 35 and 21 yards, averaging 5.4 per rush overall. RB Marlon Mack ran 5 times for 37 yards and a TD, adding 4 receptions for 26 yards on 4 targets. His target count tied for 2nd on the team, and Mack ranked 2nd along in catches. Murray caught his only target for 12 yards. RB Devine Ozigbo mixed in for 2 carries for 2 yards.

Broncos RB Chase Edmonds suffered a high-ankle sprain in Sunday's loss to the Raiders and is expected to miss "multiple weeks," according to NFL Network's Tom Pelissero. Edmonds can be dropped from all redraft rosters. The news makes RB Melvin Gordon's release even more surprising. Denver is down to RBs Latavius Murray and Marlon Mack for now. RB Devine Ozigbo is on the practice squad; RB Mike Boone is eligible to come off IR for Week 13.

As expected, Broncos RB Latavius Murray is a healthy scratch for tonight's game vs. the Colts. Expect him to make his Broncos debut next week. RB Devine Ozigbo was elevated from the practice squad today and is active. He figures to see most of his action on special teams. We're expecting RB Melvin Gordon to handle most of the backfield work, with RB Mike Boone mixing in.

Saints RB Tony Jones is expected to miss 3-4 weeks with an ankle injury suffered in Sunday's loss to the Giants, ESPN's Adam Schefter reports. Jones can be dropped from fantasy rosters. The Saints signed RB Devine Ozigbo in a corresponding move. It's now Ozigbo, Dwayne Washington and Ty Montgomery behind Alvin Kamara on the depth chart. Kamara will continue to dominate backfield work.

As expected, Jaguars RB James Robinson (ankle) is inactive for today's game against the Bears. His absence leaves Jacksonville's backfield to Devine Ozigbo and Dare Ogunbowale. Neither is a bankable fantasy play.