49ers RB Isaac Guerendo (foot, hamstring) did not practice all week and is out for Sunday’s game vs. the Dolphins. It sounds like it’s the hamstring that’s sidelining him. Guerendo’s absence leaves San Francisco down to RBs Patrick Taylor, Ke’Shawn Vaughn, and Israel Abanikanda. Taylor is the favorite for work, but it’s unclear exactly what this backfield will look like. It’s also a tough matchup against a Dolphins defense that’s limited opposing RBs to 2.8 yards per carry over the last five weeks. See where Taylor sits in the Week 16 RB Rankings.

ESPN's Adam Schefter reports that 49ers RB Isaac Guerendo is "unlikely to play" Sunday at Miami because of his hamstring injury.

49ers RB Isaac Guerendo (foot) is active for tonight's game vs. the Rams. He was listed as questionable after only getting in a limited practice on Tuesday. But Guerendo downplayed the injury throughout the week and was reportedly expected to play tonight even before getting through warmups. There have been no reports so far about the rookie's expected workload in this one. He shapes up as a risk/reward fantasy play. Check the new-and-improved Who To Start Tool to see if Guerendo makes sense for your starting lineup. RBs Patrick Taylor and Ke'Shawn Vaughn are also active for San Francisco tonight; RB Israel Abanikanda is a healthy scratch.

49ers RB Isaac Guerendo got his first start and did not disappoint. The rookie ran 15 times for 78 yards while also catching both of his targets for 50 yards. He scored twice on the ground. Guerendo injured his foot late in the game. If that doesn’t cause him to miss time, he has earned the starting role.

Bucs RB Rachaad White managed just 34 scoreless yards on 13 carries in the Week 7 loss to the Falcons. But he was busy in the passing game, hauling in all six of his targets for 65 yards. He tied with WRs Mike Evans and Chris Godwin for the team lead in catches and ranked behind only those two WRs in receiving yards. White's six targets were a solid 14.3% share. And, although the rushing production wasn't big, White at least out-carried RB Ke'Shawn Vaughn 13 to 4. It's getting tough to expect the rushing efficiency to improve. But if White can at least maintain this type of workload share, he should be able to produce as a low-end RB2 in PPR leagues.

Buccaneers RB Chase Edmonds is having an MRI today on an MCL injury that knocked him out of Sunday's win over the Bears. Edmonds missing further time could only help rookie RB Sean Tucker, who already edged the vet in Week 1 playing time. Ke'Shawn Vaughn would likely find a role with Edmonds out as well. Rachaad White remained the clear lead back in Week 2.

Bucs rookie Sean Tucker is “a bit behind” the team’s other RBs in terms of learning the offense, per beat writer Scott Reynolds. Tucker missed the entire offseason program because of a heart issue, and for now, he appears no higher than fourth on the depth chart. Reynolds calls Ke’Shawn Vaughn the current No. 2 back behind Rachaad White, with Chase Edmonds “coming on strong" at camp.

Bucs OC Dave Canales called Ke'Shawn Vaughn his #2 RB. "He’s our two, and he’s a fantastic runner," Canales said on a recent podcast appearance. "Just quick feet in the hole, sturdy build. And he’s just got a real natural feel for it." Tampa signed RB Chase Edmonds to a 1-year, $1.2 million deal in free agency, but Vaughn will at least open training camp ahead of him on the depth chart. Vaughn has underwhelmed in limited opportunities through three NFL seasons, but any #2 RB is worth paying attention to -- especially a #2 RB behind an unproven starter in Rachaad White.

Buccaneers RB Rachaad White caught all 9 of his targets for 45 yards in Sunday's OT loss at Cleveland. He added 64 rushing yards on 14 carries, controlling the backfield work with Leonard Fournette (hip) out. Ke'Shawn Vaughn claimed the only other 4 RB carries, and no other Bucs RB drew a target. The team managed just 2 offensive TDs, on passes to Chris Godwin and Ko Kieft. We'll see about Fournette's status for Week 13.

Bucs RB Leonard Fournette (hip) is listed as doubtful for Sunday's game vs. the Browns. He got in 3 limited practices this week but evidently isn't fit to play. Assuming Fournette sits, rookie Rachaad White will step in as Tampa's clear lead back against a struggling Cleveland run defense. White will be backed up by RB Ke'Shawn Vaughn and potentially RB Gio Bernard, who was designated to return from IR earlier this week.

The Bucs placed RB Gio Bernard (ankle) on IR, knocking him out for at least 4 games. He's been active the first 2 weeks but hasn't played a snap on offense. RB Ke'Shawn Vaughn figures to take over that role while Bernard is out. Leonard Fournette and Rachaad White are locked in as Tampa's top 2 RBs.

Bucs RB Ke'Shawn Vaughn is a healthy scratch for tonight's game vs. the Cowboys. Tampa is rolling with RBs Leonard Fournette, Rachaad White and Gio Bernard.

Bucs RB Gio Bernard was knocked out of Saturday's preseason opener with an ankle injury. With RB Leonard Fournette sitting, Bernard drew the start over RBs Rachaad White and Ke'Shawn Vaughn. We'll see about the severity of the ankle injury.

We're not done hearing about RB Leonard Fournette's offseason weight gain. Here's what Rick Stroud of the Tampa Bay Times had to say on the subject this week, via the Sports Day Tampa Bay podcast: “Coaches were not happy, and that’s an understatement, when (Fournette) didn’t participate in the OTAs, but then he shows up at the mandatory minicamp weighing damn near 260 [pounds]. And that’s not a good sign for a guy that you’ve just spent a three-year contract on.” There's certainly still time for Fournette to get into shape ahead of the regular season. This is a red flag worth keeping in mind, though, given Fournette's history of lower-body injuries and his Round 2 ADP.

Bucs RB Ronald Jones (ankle) is out for Sunday’s game vs. the Panthers. With RB Leonard Fournette still on IR with his hamstring injury, Tampa is down to RBs Ke’Shawn Vaughn and Le’Veon Bell. We’re expecting a committee attack, with Vaughn leading in carries and Bell in targets.

Bucs RB Ronald Jones (ankle) did not practice on Wednesday. RB Ke'Shawn Vaughn (ribs) was a full-go. It's looking like we'll get a Vaughn and Le'Veon Bell Bucs backfield vs. the Panthers this weekend.

Bucs RB Ke’Shawn Vaughn suffered a rib injury in the 4th quarter of Sunday's win over the Jets, HC Bruce Arians said. Tampa lost RB Ronald Jones to an ankle injury earlier in the game, leaving Le'Veon Bell as the team's top RB. We’ll look for updates on Vaughn and Jones on Monday.