Giants RB Saquon Barkley (ankle) is doubtful for Monday night's game against the Seahawks. That means Matt Breida should again run as New York's top back. He'll get a more favorable matchup than Week 3, when a TD made his fantasy line against the 49ers. Breida still carries limited upside but is an option for needy Week 4 fantasy lineups. Check your Team Intel page to see how Breida compares with your other options.

Giants RB Saquon Barkley (ankle) was listed as a limited participant in Thursday's practice. NFL Network's Ian Rapoport described Barkley's status for Monday night's game vs. the Seahawks as a "wait-and-see" situation, adding that Barkley "has a long way to go." We're still not projecting him to play this week but will continue to monitor his progress over the next few days.

The Giants have officially ruled RB Saquon Barkley out for Thursday night's game against the 49ers. That's been expected since news broke of his Week 2 ankle sprain. Matt Breida is expected to be the first guy up in the Week 3 backfield, but that's only enough to land him in RB4 territory in our Week 3 RB rankings. Expect Gary Brightwell and rookie Eric Gray to mix in as well for a backfield that has been limited even with Barkley through two weeks.

ESPN's Adam Schefter reports that Giants RB Saquon Barkley is expected to miss three weeks with his ankle injury. It's an "ordinary" sprain, rather than a high-ankle sprain, Schefter adds. It's all relatively good news, but fantasy owners will still need to prep to be without Barkley for the short term. Schefter's timeline would have him back for Week 6 vs. the Bills. Barkley's absence leaves the Giants' backfield to Matt Breida, Gary Brightwell, and rookie Eric Gray. Breida is the preferred fantasy add but shouldn't be considered more than a low-upside RB3 or flex.