Christian McCaffrey Questionable For Week 1

49ers RB Christian McCaffrey (calf) is listed as questionable for this weekend's game vs. the Seahawks. He was added to the injury report and limited in practice on Thursday and officially did not practice on Friday. McCaffrey was on the field going through warmups at the start of Friday's practice, though, and looked reasonably healthy. We'll surely get multiple updates on McCaffrey between now and kickoff on Sunday. Hopefully he's not a game-time decision, though, because 49ers-Seahawks doesn't kick off until 4:05 pm ET. McCaffrey's absence would leave Brian Robinson as San Francisco's lead back, although it's unclear exactly how big a role he'd be ready for after joining the team on August 22. RB Isaac Guerendo will also be available for the 'Niners, but RB Jordan James (finger) is doubtful.