Chargers Edge Khalil Mack is inactive for tonight's game against the Bengals. That's no shock after he missed all practices the past two weeks and managed to play just four snaps last week. Mack's absence can only help the playing time for Tuli Tulipulotu and Bud Dupree.

Chargers Edge Khalil Mack is questionable for the second straight week thanks to a groin injury that kept him out of practice once again. Mack missed all three practices last week before playing through a "questionable" tag last week. He made it through just 4 snaps in that game. Edge Joey Bosa, meanwhile, put in his first full practice since Week 3 on Friday and is off the final injury report for the first time since that week as well. He said Friday that they plan to increase his playing time from the 19-20 snaps of the past three games to "about 30, 30-plus."

In another clear sign that the Titans are surrendering Thursday night's game to the Cowboys, the team announced Wednesday that basically the entire defense is out or doubtful. DT Jeffery Simmons, S Amani Hooker, EDGE Bud Dupree, LB Dylan Cole and LB Zach Cunningham are out. DL Denico Autry and CB Kristian Fulton are doubtful, which is really just a wishy-washy way of saying "out." LB Monty Rice, CB Roger McCready and S Andrew Adams like just about the only playable pieces for IDP leagues.

The Titans have ruled S Amani Hooker (shoulder) and EDGE Bud Dupree (hip) out for Thursday night's game against the Packers. DT Jeffery Simmons (ankle) is questionable. He missed Sunday's win over the Broncos but returned for limited practices the past 2 days. Simmons seems to be trending toward returning for this game and will be worth using in IDP lineups if available.

The Titans have ruled DT Jeffery Simmons (ankle) out for Sunday's game against the Broncos, along with starters S Amani Hooker (shoulder), EDGE Bud Dupree (hip) and LB Zach Cunningham (elbow). Simmons is the biggest loss, both for the run defense and the pass rush. He had played through the sprain the past 2 games -- including for 81 snaps in last week's OT loss to the Chiefs. He said this week that he aggravated the ankle in that game. We'll see whether he can make it back for a Week 11 trip to Green Bay.

Titans EDGE Bud Dupree (hip), DL Jeffery Simmons (ankle), LB Zach Cunningham (elbow), S Amani Hooker (shoulder) and CB Kristian Fulton (hamstring) missed Thursday's practice. Simmons has played the past 2 weeks despite missing both practice weeks. His playing time increased last game vs. the 1 before. We'll see about the whole group Friday.

Titans DT Jeffery Simmons (ankle) and EDGE Bud Dupree (illness) are active for tonight's game against the Chiefs.

The Titans have ruled S Amani Hooker (shoulder) out for Sunday's game against the Chiefs. DT Jeffery Simmons (ankle) and EDGE Bud Dupree (illness) are questionable. Simmons missed the entire practice week for the 2nd straight time but still played through the issue for last Sunday's win at Houston. Dupree popped up on the injury report after missing Friday's workout. We'll confirm the status of both starters Sunday night. Make sure you have an insurance option if you hope to wait for Simmons in your IDP lineup.

Titans S Amani Hooker (concussion), EDGE Bud Dupree (hip) and LB Zach Cunningham (elbow) are out for Sunday's game against the Commanders.

The Titans defense practiced without 3 starters Thursday. S Amani Hooker (concussion) sat out, just a day after putting in a limited workout. That seems to indicate he's not likely to play Sunday against the Commanders. EDGE Bud Dupree (hip) and LB Zach Cunningham (elbow) each missed a 2nd straight practice. These absences would only soften a defense that doesn't present a scary matchup at full strength.

The Titans have ruled EDGE Bud Dupree (hip) out for Sunday's game against the Raiders. LB Zach Cunningham is questionable with a knee injury he suffered Thursday. That kept him off the field Friday. Neither should have factored significantly into your IDP plans. We'll check Cunningham's status Sunday.

The Titans have placed WR Julio Jones and WR Nick Westbrook-Ikhine on the COVID list. We'll see whether either guy can make it back for Sunday's game against the Dolphins, but neither should be in your Week 17 fantasy football plans. Tennessee also placed EDGE Bud Dupree on the list Monday. We'll see whether any more Titans get added through the week.

The Titans have ruled LB David Long (hamstring), LB Rashaan Evans (ankle) and EDGE Bud Dupree (abdomen). CB Janoris Jenkins (chest) is questionable after missing Thursday's and Friday's practices. EDGE Harold Landry (hamstring) and DL Jeffery Simmons (ankle) carry no injury designations into the game despite managing injuries this week. Landry spent the week limited with a hamstring issue. Simmons sandwiched a missed Thursday's practice between 2 limited workouts. Both look fine to use in IDP lineups, though.

Titans LB Bud Dupree is inactive for today's game against the Jaguars. DL Denico Autry is active after arriving questionable.

Titans OLB Bud Dupree (knee) is active for today's game against the Colts. He entered questionable and still doesn't seem 100% back from last year's ACL tear. We'd try not to use him in IDP lineups. But he's available if you're in need.

Titans OLB Bud Dupree is questionable for Sunday's game against the Colts because of knee trouble. He played through a questionable tag last week for 72% of the snaps. This week, however, found him missing practice both Wednesday and Friday. Dupree put in 2 limited workouts before playing Week 2. We'll update his status Sunday morning, but Dupree -- coming off a late 2020 ACL tear -- shouldn't be anywhere near your IDP lineups.

Titans LB Jayon Brown (hamstring) is inactive for today’s game against the Seahawks. David Long figures to start in his place next to Rashaan Evans. OLB Bud Dupree (knee) is active but a low-end IDP option at best.

Titans LB Jayon Brown (hamstring) is questionable for Sunday's game at Seattle. He missed practice Friday with a hamstring injury that didn't affect his participation either of the previous 2 days. That progression doesn't seem to bode well for Brown's game status. OLB Bud Dupree is also questionable with a knee issue. We wouldn't be using him in IDP lineups even if he's active.

The Titans have placed rookie CB Caleb Farley on the non-football injury list and OLB Bud Dupree on the PUP list to begin training camp. Dupree is still working back from the early December right ACL tear that ended his 2020 season. Farley has had 2 back surgeries since his last action at Virginia Tech in 2019. Both players figure to be important pieces for a Tennessee defense that needs to improve on last year's performance. We'll see how they progress through the summer.