Texans GM Nick Caserio wouldn't say Wednesday whether RB Joe Mixon (foot/ankle) will play at all this year. "We'll see, we'll take it one day at a time," Caserio said. Mixon will miss at least the first four games of the season on the reserve/non-football injury list. "Once we get through four weeks, we'll evaluate it at that time," Caserio added.

The Houston Texans have placed RB Joe Mixon (ankle) on the reserve/non-football injury list, according to Adam Schefter of ESPN. He’ll miss at least the first four games.

Texans RB Joe Mixon hasn't been on the field in a while, and we've seen alternating reports of ankle injury and foot injury. So which is it? Seems like some sort of combo.

Texans RB Nick Chubb (concussion) participated in practice again on Tuesday and split first-team reps, according to Aaron Wilson of KPRC2 Houston.

Texans RB Nick Chubb missed practice on Wednesday. Chubb "took a hard shot to the head" on Tuesday and was checked for a concussion, per Aaron Wilson of KPRC 2 Houston. In his place, Dameon Pierce – who recently missed time with a quad injury – saw first-team reps. We'll see when Chubb returns to the field. Currently, the former Brown cracks the top-50 of our updated RB rankings.

Texans RB Joe Mixon is expected to miss "an extended period of time with a frustrating foot injury," according to NFL Network's Ian Rapoport. Mixon has been dealing with an injury for much of the offseason, but it was previously reported as a right ankle. It's unclear if this is a separate injury, or if the initial reporting was bad. Regardless, it sounds like Mixon will miss all of training camp, and "there's a chance" he won't available for Week 1, per Rapoport. Mixon "will be re-evaluated closer to the season to determine his availability," Rapoport adds.

Texans RB Joe Mixon (ankle) is listed as questionable for Saturday's Divisional Round game vs. the Chiefs. After being added to the injury report and limited on Wednesday, Mixon did not practice on Thursday. He seems legitimately iffy for this one. Mixon's absence would leave Dameon Pierce as Houston's lead back and deal a big blow to the Texans' chances of pulling the upset in Kansas City. We'll keep you updated on Mixon's status and get Houston's inactives around 3 pm ET on Saturday.

Texans RB Joe Mixon was added to Wednesday's injury report and limited in practice with an ankle. We don't have any other details on his status right now. We'll see if Mixon practices on Thursday and then how he's listed on the final injury report for Saturday's Divisional Round game vs. the Chiefs. Mixon's absence would leave Dameon Pierce as Houston's lead back -- and likely mean a pass-heavier game plan.

Texans RB Dameon Pierce (groin) is out for Sunday night’s game vs. the Lions. He’ll be replaced again by RB J.J. Taylor, who is not a fantasy option. RB Joe Mixon should be in for another big workload.

Texans RB Dameon Pierce (groin) is out for Thursday night's game vs. the Jets. He's carried just 11 times over the past three weeks with RB Joe Mixon back, including three carries over the last two games, so there's little fantasy impact here. Mixon already projected to be super busy against the run-funnel Jets.

The Texans are trading RB Cam Akers to the Vikings for a swap of conditional Day 3 draft picks in 2026. Houston's sending Akers and a conditional seventh-rounder to the Vikings for a conditional sixth-rounder, according to NFL Network's Tom Pelissero.

Texans RB Joe Mixon (ankle) remained sidelined for Wednesday's practice. HC Demeco Ryans labeled him "week to week" on Monday, so fantasy owners should not be expecting Mixon back for this weekend's game vs. the Patriots. RB Dameon Pierce (hamstring) was limited on Wednesday and is on track to return for Sunday's game. In that case, you should avoid Houston's backfield in Week 6 fantasy lineups.

Texans HC Demeco Ryans said Monday that RB Joe Mixon (ankle) is "definitely improving" but wouldn't say whether Mixon will be back for this weekend's game vs. the Patriots. Mixon returned to Friday's practice ahead of Week 4 but did not practice at all this past week, so it looks like he suffered a setback.

Texans RB Dameon Pierce (hamstring) is inactive for today's game vs. the Bills. That again leaves the backfield to Cam Akers, Dare Ogunbowale, and J.J. Taylor. Akers figures to lead in touches but ceded carries to Taylor and passing-down snaps to Ogunbowale last week.

Texans RB Dameon Pierce (hamstring) is not expected to play vs. the Bills today, according to ESPN's Adam Schefter. Pierce just returned to a limited practice on Friday after missing the last three games, so it's no surprise that he's not ready yet. With RB Joe Mixon (ankle) also out, Houston will again roll with RBs Cam Akers, Dare Ogunbowale, and J.J. Taylor.