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Isaac Guerendo Injury History & Analysis

Isaac Guerendo

Isaac Guerendo
Player Profile
RB SF

Height

6'0"

Weight

221 lbs.

Experience

1 yrs.

Bye

9

Birthday

Jun 28, 2000

Age

24.8

College

Louisville

NFL Draft Pick

2024 - Rd 4, Pk 129

Isaac Guerendo's Injury Guide

Unknown Risk

Chance of Injury in 2025

-

% chance misses at least 2 quarters

Chance of Injury per Game

-

1- 17√1-% Inj/Season

Projected Games Missed 2025

Durability

Ability to produce despire relatively minor injuries. 5 being most durable

Injury analysis powered by Draft Sharks Injury Guide, formerly Sports Injury Predictor

Isaac Guerendo's Injury Status

No active injuries.

Isaac Guerendo Injury History

Date League Injury Games Missed Details
Jan 5, 2025
NFL Knee MCL Pull
Grade 1
- Guerendo suffered knee and ankle injuries in the regular-season finale loss to the Cardinals.
Dec 18, 2024
NFL Thigh Hamstring Sprain/Pull
Unspecified Grade 1
1 Guerendo was ruled out for Week 16's game at Miami due to a hamstring injury.
Dec 8, 2024
NFL Pedal Foot Sprain
Grade 1
- Guerendo suffered a foot injury in the fourth quarter of Week 14's game vs. the Bears.
Jul 24, 2024
NFL Thigh Hamstring Sprain/Pull
Unspecified Grade 1
- Guerendo injured his hamstring during training camp practice but recovered in time for the preseason game against Las Vegas.
Oct 2, 2021
NFL Pedal Ankle Ligament
Tear Grade 3
8 Guerendo suffered a season-ending ankle injury against Michigan. He was out for the spring
How do Injuries impact your draft strategy?

For us, it's 1/17th of the equation. Hear us out.

The Draft War Room is the only live-sync draft tool that monitors 17 crucial in-draft indicators, including injury likelihood… and adapts to show you which players to pick throughout your draft.

Isaac Guerendo Injury News

Vikings Get Jordan Mason to Play RB2

12:56am EDT 3/16/25

Vikings Get Jordan Mason to Play RB2

The 49ers are trading RB Jordan Mason to the Vikings, according to multiple reports. Mason is getting a two-year, $7 million deal with Minnesota that carries a max value of $12 million. The Niners are getting back just a 2026 sixth-rounder and a pick swap in this year's draft, according to NFL Network.

ESPN's Adam Schefter reports that the 49ers have tendered RB Jordan Mason at the second-round level. That still leaves Mason open to sign with other teams, but any team that signs Mason would have to send San Francisco a second-round pick.

49ers RB Isaac Guerendo injured his left leg on the first drive of Sunday's game vs. the Cardinals. He was quickly ruled out for the rest of the game with knee and ankle injuries. We'll update Guerendo's status when we know more, but this looks like a serious injury.

49ers WR Deebo Samuel (rib, wrist) is out for Sunday's game vs. the Cardinals. Although he's had a disappointing season, Samuel has averaged 5.0 targets and 3.0 carries over the last five games. So his absence leaves extra opportunity for WRs Jauan Jennings and Ricky Pearsall and RB Isaac Guerendo.

49ers RB Isaac Guerendo (foot, hamstring) is not listed on the final Week 17 injury report. He was a full participant in Saturday's practice and seems ready to take back over as San Francisco's clear lead back in Monday night's game vs. the Lions. Guerendo checks in 17th in the Week 17 RB Rankings.

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Video: Week 16 Preview

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Breece Hall's off the injury report. Isaac Guerendo, Alvin Kamara and others are hurt. Reacting appropriately to each situation could win you Week 16.

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10:52pm EST 12/6/24

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