Cardinals QB Jacoby Brissett completed an NFL-record 47 passes in Sunday's loss to the 49ers. Brissett attempted 57 throws in the lopsided defeat, logging 32 of those in the second half. His team didn't fall quite as hopelessly behind San Francisco as it did Seattle the week before. But the Niners did score the first 13 points of the game and lead 25-10 at the half. Brissett went 20-of-25 passing before the break. He finished with 452 yards, 2 TDs, and 2 INTs. Brissett sits third among fantasy QBs for the week ahead of Monday night's game.

Cardinals WR Marvin Harrison underwent surgery for appendicitis and will be out for Sunday's game against the 49ers and potentially longer, according to both NFL Network's Ian Rapoport and ESPN's Adam Schefter. We'll look for a more concrete target for Harrison's return, but he's worth keeping stashed in all fantasy leagues for now.

QB Jacoby Brissett endured easily his roughest outing Sunday since taking over for the injured Kyler Murray. He took five sacks in the loss to the Seahawks and lost a pair of fumbles that each got returned for TDs (both by Edge Demarcus Lawrence). Brissett completed just half of his 44 pass attempts for an offense that didn't score until it already trailed 35-0, and even then thanks to Sam Darnold turning the ball over at his own 2-yard line. But Brissett still managed 258 yards and 2 TDs passing, plus another 31 yards on four rushing attempts. He heads into Monday night with the ninth-best fantasy total among QBs for the week, according to ESPN scoring.

Cardinals QB Kyler Murray was placed on Injured Reserve with his mid-foot sprain. Murray appeared close to returning last week, but was inactive in Week 9. QB Jacoby Brissett was announced as the starter for Week 10, but he steps in for the next four games as the Cardinals starting QB.

Cardinals HC Jonathan Gannon announced Tuesday that he'll start QB Jacoby Brissett on Sunday at Seattle. But he stopped short of extending the decision beyond this week.

Cardinals QB Kyler Murray (foot) is inactive for tonight's game vs. the Cowboys. QB Jacoby Brissett makes his third straight start. He played reasonably well in his first two and gets a cushy matchup in this one against a defense supplying a 47.6% boost to QB fantasy production.

Cardinals QB Jacoby Brissett will start Monday night's game vs. the Cowboys, according to ESPN's Adam Schefter. QB Kyler Murray, who has been limited in practice this week, is "making progress" in his recovery from his sprained foot and "could have a role" against Dallas. We hear about teams potentially playing two QBs every so often -- and it rarely actually happens. We're projecting Brissett to play every snap in this cushy matchup, making him a strong QB2 and even a low-end spot-starter in 1-QB leagues. The news doesn't tangibly impact either WR Marvin Harrison Jr. or TE Trey McBride. Both guys are strong Week 9 starts.

Cardinals QB Kyler Murray (foot) was on the field for the start of Friday's practice, but QB Jacoby Brissett was throwing to the first-team WRs, according to ESPN's Josh Weinfuss. HC Johnathan Gannon expressed optimism about Murray's Week 9 status on Thursday morning, but Murray was limited in practice later that day. It's now looking like Brissett will get another start on Monday night vs. Dallas. Brissett played well in two starts prior to the Cardinals' bye, throwing for 599 yards, four TDs, and one INT on 7.5 yards per attempt. He's at least a strong QB2 in this dream matchup against the Cowboys and could even be a serviceable QB1 spot starter.

Cardinals QB Kyler Murray (foot) is inactive for Sunday’s game vs. the Packers. ESPN’s Adam Schefter reported Saturday night that Murray is expected back after the team’s Week 8 bye. QB Jacoby Brissett makes his second straight start today after posting a 320-2-1 passing line vs. the Colts last week. The matchup is much tougher this week, so Brissett is just a low-end QB2. But he keeps TE Trey McBride and WR Marvin Harrison Jr. fantasy viable.

The Cardinals are "planning to start" QB Jacoby Brissett vs. the Packers tomorrow, according to NFL Network's Ian Rapoport. That's the vibe we've gotten all week, with Murray remaining limited in practice. Brissett played well against a banged-up Colts secondary last week, throwing for 320 yards and two TDs. But he faces a much tougher test this weekend vs. the Packers. Brissett is just a low-end QB2 in fantasy lineups, although he doesn't project as a huge downgrade from Murray for WR Marvin Harrison Jr. and TE Trey McBride

Cardinals QB Kyler Murray (foot) is listed as questionable for Sunday’s game vs. the Packers. He was limited in practice all week. We’re tentatively expecting QB Jacoby Brissett to get another start this weekend but will keep you updated on the situation. A less-than-100% Murray would be a shaky fantasy play if he starts vs. a tough Green Bay defense.

Cardinals QB Kyler Murray (foot) is inactive for today’s game against the Colts. NFL Network’s Ian Rapoport said Saturday night that Murray could miss more than just this game with a mid-foot sprain. We’ll track his status this coming week. QB Jacoby Brissett gets the start today. He’s a downgrade for the offense, but TE Trey McBride remains a must-start, while WR Marvin Harrison Jr. remains a fine lower-end fantasy play.

A final decision on QB Kyler Murray (foot) will come on Sunday, but the Cardinals are "preparing" for QB Jacoby Brissett to start vs. the Colts, according to NFL Network's Ian Rapoport. Murray is dealing with a mid-foot sprain that kept him to just a limited practice on Friday this week. "There is a possibility Murray is out more than this week, as pushing it can cause an aggravation," Rapoport adds.

Cardinals QB Kyler Murray (foot) is listed as questionable for this weekend’s game against the Colts. He only got in a limited practice on Friday. HC Jonathan Gannon said Friday morning that the team needs to see how Murray progresses over the next couple of days before determining his availability for this one. His rushing ability figures to be impacted if he does suit up, which would leave Murray as a shaky Week 6 fantasy play. QB Jacoby Brissett would draw the start if Murray can’t go. It’d be a significant downgrade for WR Marvin Harrison Jr. and TE Trey McBride.

Cardinals QB Kyler Murray (foot) missed his second straight practice on Thursday. He played through this injury last week but seems to be in real danger of missing Sunday's game vs. the Colts. We'll see if Murray practices on Friday and then how he's listed on the final injury report. If Murray can't go, Arizona would turn to QB Jacoby Brissett. He started the first five games of last season for the Patriots, completing just 58.5% of his passes at 5.2 yards per attempt. Brissett would be a tangible downgrade for WR Marvin Harrison Jr. and TE Trey McBride.

Cardinals QB Kyler Murray suffered a foot injury in the third quarter of Sunday's game vs. the Titans. He headed back to the locker room and is officially questionable to return. We'll update Murray's status when we know more. QB Jacoby Brissett replaced Murray.

Update: Murray returned after missing just a few plays.