Niners QB Brock Purdy threw for 200 yards and 3 TDs in Sunday's win over the Cardinals. The game marked Purdy's first action since Week 4, because of turf toe. He completed 19 of 26 passes in the lopsided victory, including a 10-of-15 first half (for 123 yards and 2 TDs). Purdy found TE George Kittle for scores from 30 and 4 yards out and hit RB Christian McCaffrey for a 9-yard score early in the second quarter.

49ers QB Brock Purdy (toe) will start Sunday's game vs. the Cardinals, HC Kyle Shanahan said Thursday. Purdy's toe evidently responded well to the increased work in Wednesday's practice. It's worth remembering that Shanahan previously said that Purdy likely wouldn't be back to 100% at any point this season. Don't expect his rushing production to reach the 21.5 yards per game he averaged last year. But Purdy can still help fantasy teams the rest of the way. He tallied 277-2-2 and 309-2-2 passing lines in his only two games earlier this season. Purdy gets fine matchups the next two weeks against the Cardinals and Panthers, followed by a tougher draw vs. the Browns and then a Week 14 bye. Purdy then closes the season with three nice spots vs. the Titans, Colts, and Bears.

49ers QB Brock Purdy (toe) remained limited in Wednesday's practice. But HC Kyle Shanahan said before the workout that it'd be an "aggressive" practice for Purdy, with the goal of ramping him up to play vs. the Cardinals this weekend. His availability will likely come down to how the toe responds to the increased work -- although Shanahan has already admitted that Purdy likely won't be back to 100% at any point this season. We'll keep you updated on his status over the next few days, but we're now projecting Purdy to start vs. the Cardinals on Sunday.

49ers QB Brock Purdy (toe) is inactive for today’s game vs. the Rams. Multiple reports over the last couple days have Purdy potentially back for next week. But QB Mac Jones gets another start today.

49ers QB Brock Purdy (toe) could return for next week's game vs. the Cardinals, according to NFL Network's Mike Garafolo. "He's getting closer," Garafolo says. "The 49ers want to make sure that he doesn't suffer another setback here. He's their franchise QB." Purdy has seemingly been close to a return for a few weeks now, so we wouldn't go locking him back into Week 11 fantasy lineups. But we'll keep tabs on his progress next week -- and see if he can get in some full practices after being limited the last few weeks.

49ers QB Brock Purdy (toe) remained limited in practice all week and is listed as questionable for Sunday’s game vs. the Rams. Purdy might be available as the backup, HC Kyle Shanahan said, but QB Mac Jones will get the start. Jones posted a 342-2-0 line vs. the Rams earlier this season, although it took him 49 attempts to get there.

49ers QB Brock Purdy (toe) was once again limited in Wednesday's practice. HC Kyle Shanahan said he'd like to get Purdy more first-team reps in practice this week but didn't say whether he has a chance to return for this weekend's game vs. the Rams. At this point, it seems more likely that QB Mac Jones gets another start. But we'll keep you updated on the situation.

49ers QB Mac Jones will start Sunday’s game vs. the Giants, HC Kyle Shanahan said Friday. QB Brock Purdy (toe) “has a chance” to be available as the backup after another limited week of practice. Jones has cooled off the last two games against tough Falcons and Texans defenses, but he has a chance to bounce back on Sunday vs. the Giants’ 23rd-ranked QB defense.

49ers QB Brock Purdy (toe) was limited in Wednesday's practice, as he's been for the last two weeks. HC Kyle Shanahan suggested earlier this week that Purdy has a chance to return for Sunday's game vs. the Giants. We'll keep you updated on his status.

49ers HC Kyle Shanahan said, "I don't think it's a long shot" when asked if QB Brock Purdy (toe) will be able to play vs. the Giants this weekend. Um, we guess we'll take that? "I think it's too early to say," Shanahan added. "I know he is doing better and we'll see how he's doing Wednesday. Hopefully if he's doing good, he'll get in some reps." Purdy has been limited in practice the past two weeks. QB Mac Jones, meanwhile, has cooled off over the last two weeks. totaling just 345 yards with two TDs and two INTs. We'll keep you updated on Purdy's progress throughout the week.

49ers QB Brock Purdy (toe) is out for Sunday’s game vs. the Texans. He was limited in all three practices for the second straight week. We’ll see if Purdy can make it back for Week 9’s game against the Giants. QB Mac Jones makes his sixth start of the season in a tough test against Houston’s top-ranked QB defense. That knocks Jones out of consideration in 1-QB fantasy leagues.

49ers HC Kyle Shanahan said Monday that it'd be "a reach" for QB Brock Purdy (toe) to play against the Texans this weekend, according to insider Jerry McDonald. Purdy was limited in practice all last week, but the team continues to play it safe with his return from the second iteration of this toe injury. QB Mac Jones will likely make his sixth start of the season on Sunday. He was cooled off by a tough Falcons defense in Week 7 and gets another challenging matchup against Houston in Week 8.

49ers QBs Brock Purdy (toe) is out for Sunday night’s game vs. the Falcons. He was limited in practice all week, potentially setting him up for a Week 8 return. QB Mac Jones gets another start this weekend. He ranks 17th among QBs in fantasy points per game and has finished top-15 in three of four starts. But he gets a surprising Falcons defense that ranks third in adjusted fantasy points allowed to QBs.

49ers QBs Brock Purdy (toe) and Mac Jones (knee, oblique) were limited in Wednesday's practice. HC Kyle Shanahan said that Purdy was more limited than Jones. We're tentatively projecting Jones to get another start vs. the Falcons on Sunday night, but we'll continue to keep you updated on the situation.

ESPN's Adam Schefter reports that 49ers QB Brock Purdy (toe) and WR Ricky Pearsall (knee) have a "chance" to return for next weekend's game against the Falcons. Both guys missed all three practices this week and were ruled out on Friday. We'll keep tabs on their progress this coming week.

The injury-ravaged 49ers officially ruled QB Brock Purdy out for San Francisco's Week 6 game against the Tampa Bay Buccaneers. Purdy did some work on the side at practice on Friday, but was never close to returning. Mac Jones will be under center once again for the Niners.

49ers QB Brock Purdy (toe) did not practice on Wednesday. He suffered a setback in Week 4 and seems unlikely to play against the Buccaneers on Sunday. The Niners have no reason to rush Purdy back with how well QB Mac Jones is playing. It looks like Jones will again be without Ricky Pearsall, George Kittle, and potentially Jauan Jennings this week, which is keeping him outside the top 12 in our QB Rankings. But he has enough upside to be in consideration as a spot starter in 1-QB fantasy leagues.

49ers QB Mac Jones completed 33 of 49 passes (67%) for 342 yards (7.0 YPA), two TDs, and 0 INTs in Thursday night's overtime win over the Rams. More impressive: He did it without Ricky Pearsall, Jauan Jennings, Brandon Aiyuk, or George Kittle. Jones fed RB Christian McCaffrey eight times for 82 yards and a score. But he also hooked up with WR Kendrick Bourne for 10 completions and 142 yards. Jones' other TD went to TE Jake Tonges, who finished with seven grabs for 41 yards. Jones' timing and ball placement were on point all night. And he stood tall in the pocket amidst countless big hits from a strong Rams pass rush. It was an impressive showing.

49ers QB Brock Purdy suffered a setback with his toe injury last week, according to NFL Network's Ian Rapoport. Purdy wasn't close to playing vs. the Rams on Thursday night, per Rapoport, and "could miss additional games." We'll keep tabs on Purdy's status when the 49ers get back to work next week. QB Mac Jones has played well enough so far that the 49ers can be cautious with Purdy (although they evidently weren't cautious enough the first time around). San Francisco's bye is not until Week 14.

49ers QB Brock Purdy (toe) and WRs Ricky Pearsall (knee) and Jauan Jennings (ankle, ribs) have all been ruled out for Thursday night's game against the Rams. It doesn't sound like any of their injuries are serious, but the short week did them no favors. We'll see if they can make it back for Week 6. QB Mac Jones makes another start vs. the Rams this week. He played well in Week 2 and 3 starts, completing 66% of his passes at 7.0 yards per attempt with 4 TDs vs. 1 INT. He'll be working with a rag tag group of pass catchers on Thursday night, though. The WR corps figures to be led by Kendrick Bourne, Demarcus Robinson, and Skyy Moore, while Jake Tonges again leads the TE room. We'd try not to mess with any of these guys in Week 5 fantasy lineups. RB Christian McCaffrey will be very busy yet again.