Bills WR Isaiah McKenzie (concussion) is listed as questionable for this weekend's game vs. the Steelers. He got in limited practices on Thursday and Friday but still has work to do to clear protocol. We should get another update on McKenzie by Sunday morning. With WR Jamison Crowder and Jake Kumerow out with their ankle injuries, McKenzie's absence would leave rookie Khalil Shakir as Buffalo's #3 WR.
Titans WR Treylon Burks (toe) is out for Sunday’s game vs. the Commanders, as expected. The rookie figures to miss multiple weeks with his turf toe. Burks’ absence leaves Robert Woods and Nick Westbrook-Ikhine as Tennessee’s top 2 WRs, with Kyle Phillips likely taking over in the slot.
Falcons HC Arthur Smith said Friday that TE Kyle Pitts' hamstring injury is "not expected to be long-term." Smith, per ESPN's Michael Rothstein, said Pitts "woke up more sore than usual" after last week's game, so the team is being cautious in holding him out this Sunday. We'll see if Pitts is able to make it back for Week 6.
The Bills have ruled S Jordan Poyer out for Sunday's game against the Steelers because of his rib injury. S Damar Hamlin started in place of S Micah Hyde last week and should remain in the lineup. We'll see who replaces Poyer, who didn't miss a snap in the Week 4 win over Baltimore. Jaquan Johnson started next to Hamlin in Week 3, when Buffalo last went without both starting safeties. He looks like the best bet to join Hamlin again. We'd try to look elsewhere for IDP options in most cases.
Colts HC Frank Reich said after Thursday night's win over the Broncos that he's "optimistic" RB Jonathan Taylor (ankle) can return next week, per The Athletic's Zak Keefer. We'll keep an eye on Taylor's practice participation next week, as well as Nyheim Hines' after he sustained a concussion.
Commanders HC Ron Rivera said Friday that RB Brian Robinson "had a good week" of practice. "We're pretty fired up," Rivera added. "We'll go through tomorrow morning and see how he is and then decide." It sounds like Robinson has a shot to play vs. the Titans this weekend. We wouldn't use him in Week 5 fantasy lineups, but his return would put a significant dent in RB Antonio Gibson's fantasy value.
Commanders WR Jahan Dotson (hamstring) is out for Sunday's game vs. the Titans. No surprise after HC Ron Rivera said earlier this week that Dotson would miss "a week or 2." He'll be replaced by some combination of WRs Dyami Brown and Cam Sims -- but WRs Terry McLaurin and Curtis Samuel should pick up extra targets.
Bucs TE Cameron Brate (concussion) is out for Sunday's game vs. the Falcons. That leaves Cade Otton as Tampa's likely lead TE. The rookie ran 32 pass routes in last week's loss to the Chiefs, hauling in 3 of 4 targets for 29 yards. You should be able to do better than Otton in season-long leagues, but he's an intriguing flier in DFS.
Falcons TE Kyle Pitts (hamstring) is out for Sunday's game vs. the Bucs. We'll see if he can make it back for Week 6. His absence leaves Parker Hesse as Atlanta's top TE, with Anthony Firkser behind him. Avoid that situation in fantasy lineups. The Falcons figure to lean on their run game for as long as they can on Sunday. When they do take to the air, WR Drake London should dominate targets.
Bills TE Dawson Knox (foot, hamstring) is out for Sunday's game vs. the Steelers. He's been banged up all season, so the week off should be good for him. Knox's absence leaves Buffalo with TEs Quintin Morris and Tommy Sweeney. Morris is the better bet for targets but would be a desperation fantasy play.
Giants WR Wan'Dale Robinson (knee) is out for Sunday's game vs. the Packers in London. He put in limited practices on Wednesday and Thursday but was sidelined on Friday. That doesn't bode well for Robinson's chances of returning in Week 6. With WRs Kadarius Toney and Kenny Golladay also out this weekend, New York is down to WRs Richie James, David Sills, Darius Slayton and Marcus Johnson.
Giants QB Daniel Jones (ankle) isn't listed on the final injury report and will start Sunday morning's game vs. the Packers. Jones put in limited practices on Wednesday and Thursday and a full workout on Friday. It's still tough to believe that he'll have his usual mobility this weekend, which takes away most of whatever fantasy appeal Jones has. QB Tyrod Taylor (concussion) is out for Week 5, leaving QB Davis Webb as the backup.
Giants WRs Kadarius Toney (hamstring) and Kenny Golladay (knee) did not travel with the team to London and are out for Sunday morning's game vs. the Packers. Toney got in a limited practice on Wednesday but then didn't practice on Thursday. Golladay missed both days with his MCL sprain. We'll see if they can make it back for Week 6.
Broncos LB Josey Jewell left in the 1st half of Thursday night's game against the Colts with a knee injury and was then ruled out. We'll see about the specific diagnosis and expected return timeline. Alex Singleton filled in and got full playing time when Jewell missed the 1st 2 games of the year. We'll see whether he's the guy again if Jewell misses further time, or if LB Jonas Griffith gets more snaps.
Colts RB Nyheim Hines sustained an apparent concussion on the 1st series of Thursday night's game vs. the Broncos. Hines stumbled as he tried to get off the field. So, after what happened recently with Dolphins QB Tua Tagovailoa, don't expect to see Hines back on the field tonight. That'll leave the Colts with RBs Phillip Lindsay and Deon Jackson.
Update: Hines has a concussion and is out for the rest of the game.
Chiefs K Harrison Butker (ankle) did not practice on Thursday. Fantasy owners can't be banking on him playing vs. the Raiders on Monday night. Matthew Wright will again kick for Kansas City if Butker is out.
Raiders WR Hunter Renfrow (concussion) put in a full practice on Thursday. Barring a setback, he'll return for Monday night's game vs. the Chiefs.
Ravens WR Rashod Bateman (foot) missed his 2nd straight practice on Thursday. At this point, he seems unlikely to play vs. the Bengals on Sunday night. Bateman's absence would leave Baltimore with WRs Devin Duvernay, Demarcus Robinson, James Proche and Tylan Wallace.
Cardinals K Matt Prater (hip) is out for Sunday's game vs. the Eagles, HC Kliff Kingsbury said. K Matt Ammendola, who kicked for the Chiefs in Weeks 2 and 3, will step in for Prater. We'd look elsewhere for your fantasy lineups.
Cardinals WR Marquise Brown (foot) returned to a limited practice on Thursday. He should be fine for this weekend's game vs. the Eagles.
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